Tuesday, March 24, 2026

En-Bloc HoLEP Manual — The Definitive Guide to Prostate Enucleation



After performing over 10,000 prostate enucleations and training urologists in more than 50 countries, I have published what I believe is the most comprehensive resource available on en-bloc HoLEP: the Manual de Enucleación Prostática HoLEP en Bloque.

354 pages distilling two decades of real surgical experience. Not abstract theory. Real cases, step-by-step technique, complication management, and everything a urologist needs to master this procedure.

Why an en-bloc HoLEP manual?

Benign prostatic hyperplasia (BPH) affects over 50% of men older than 60. Holmium laser enucleation of the prostate — HoLEP — has established itself as the gold standard for large prostates. Both EAU and AUA guidelines recommend it as a first-line option regardless of prostate size.

En-bloc HoLEP takes this a step further. Instead of enucleating the prostate in multiple fragments (the classic trilobular approach), en-bloc technique removes the entire adenoma in a single piece. The advantages are clear:

  • Shorter operative time — fewer steps, less tissue manipulation
  • Superior hemostasis — better visualization throughout the procedure
  • More intuitive learning curve — the anatomical plane guides the surgeon

What you will find in this manual

This is not a theoretical textbook. It is a surgical manual built in the operating room:

  • Detailed surgical anatomy — the dissection planes that make the difference between a clean enucleation and a complicated one
  • Step-by-step technique — from initial incision to morcellation, with intraoperative images
  • Complication management — what to do when things do not go as planned
  • Learning curve — how to structure your training, how many cases you need, which mistakes to avoid
  • Special cases — prostates over 200 grams, patients on anticoagulants, complex anatomies
  • Outcomes and evidence — long-term follow-up data from thousands of patients

Who is this book for

Any urologist looking to incorporate HoLEP into their practice or improve their results with the en-bloc technique. Whether you are starting your learning curve or already experienced with the trilobular approach, this manual provides the perspective of someone who has operated in over 50 countries and trained hundreds of urologists live.

It is also a useful reference for urology residents who want to understand the technique before facing the laser for the first time.

Book details

  • Title: Manual de Enucleación Prostática HoLEP en Bloque
  • Author: Fernando Gómez Sancha
  • Publisher: Simed Software
  • Pages: 354
  • ISBN: 978-84-09-42726-0
  • Edition: 1st edition

Where to get it

The experience behind the manual

I have spent over 20 years refining the en-bloc HoLEP technique. I have operated in more than 50 countries — from university hospitals in Europe and the Americas to surgical centers in Asia and Africa. Every live surgery, every complex case, every question from a colleague in training has contributed to shaping this manual.

At ICUA, our center in Madrid, we perform HoLEP as our reference procedure. The results speak for themselves: reoperation rates below 1%, average catheterization of 24 hours, and patients recovering their quality of life within days.

This manual is my way of sharing everything I have learned. If you perform HoLEP or are considering adding it to your practice, I hope you find it as useful as it would have been for me at the beginning of my career.

Dr. Fernando Gómez Sancha
Co-owner of ICUA — Clínica CEMTRO, Madrid
@fgomsan | LinkedIn

Saturday, March 21, 2026

My professional journey: 32 years in urology, 52 countries, 10.000+ procedures

Dr. Fernando Gómez Sancha · Medical Director, ICUA · Clínica CEMTRO, Madrid, Spain
Last updated: March 2026

I have spent 32 years in urology. I began my residency at Hospital de la Princesa in Madrid in 1994, completed my training at the Institute of Urology in London under Prof. Mundy, and in 2002 founded ICUA with my brother Santiago. We currently operate across 6 hospitals in Madrid, Cádiz, Jaén and Seville.

Since then, my career has revolved around two things: operating and teaching. I have performed over 10,000 laser prostate enucleation procedures — first with GreenLight (photoselective vaporisation and GreenLEP), then with holmium (en bloc HoLEP with early apical release). I have operated or provided training in 52 countries, and more than 600 urologists from around the world have visited our operating theatre to learn the technique.

This interactive timeline captures that journey. It is built from the real data of this blog, my Twitter archive, and my scientific publications — over 2,400 documented events between 2002 and 2026. You can filter by category (surgery, congresses, training, publications), by year, and watch how our international reach has expanded over time using the animated map.

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International reach

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2026

Professional activity by year (2,445 documented events)

Surgery Congresses Training Publications

Milestones & activities

The technical evolution

My path in laser prostate surgery has followed a constant evolution. I started with GreenLight photoselective vaporisation in 2003, developed the GreenLEP technique (green laser enucleation) which I first presented as a video at the EAU congress in 2010 and published as a full paper in World Journal of Urology in 2015, and since 2011 have been working with the holmium laser to perfect en bloc enucleation with early apical release — the technique we perform daily at ICUA and have published in series of 137, 754, and 6,193 patients.

Training as a mission

I have always believed that every urology department in the world should be able to offer endoscopic enucleation to its patients. Since 2007, our training programme at ICUA has received over 600 visiting urologists. Many of them now perform enucleation routinely at their own centres, and several have published their own results with the technique.

In 2010 I began my collaboration with the Hill Clinic in Sofia, Bulgaria, which has become another reference centre for enucleation training, with over 4,000 laser procedures performed there.

The manual

In 2026 I published the En Bloc HoLEP Manual (ISBN 978-84-09-81888-4), a 352-page book born from the questions and challenges that visiting surgeons raise in the operating theatre. It is not an evidence-based manual in the classical sense — it is an experience-based manual drawn from over 10,000 cases.

Contact

If you are a urologist interested in training in en bloc HoLEP, or a patient looking for a surgeon with proven experience, you can reach us at:

📞 +34 91 435 28 44 · ✉ icua@icua.es
Coordination: Vanesa Cuadros · vcr@icua.es

Related articles

→ What Is HoLEP? A Complete Guide to Holmium Laser Enucleation of the Prostate
→ En Bloc HoLEP with Early Apical Release: The Gómez Sancha Technique
→ HoLEP Training: Courses, Proctoring and the ICUA Training Programme